Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences

Katschinski, Dörthe, Prof. Dr.


  • Since 2006 Professor for Physiology (W3), University Medical Center, Göttingen
  • 2003 – 2006 Independent Junior Group Leader, University of Halle (BMBF funded)
  • 2001 Habilitation
  • 1998 – 2002 PostDc, Department of Physiology, University of Lübeck
  • 1996 – 1998 Postdoctoral Fellowship (DFG funded), University of Wisconsin, USA
  • 1995 – 1996 Junior doctor, Department Internal Medicine, University of Lübeck
  • 1994 MD thesis (Dr. med.), University of Lübeck
  • 1987 – 1994 German Medical licensing exam, University of Lübeck




Major Research Interests

Hypoxia sensing, signalling and adaptation

Homepage Department/Research Group
https://hkp.umg.eu


Selected Recent Publications


  • Jatho, A., Zieseniss, A., Brechtel-Curth, K., Yamamoto, A., Coleman, M.L., Vergel Leon, A.M., Biggs, D., Davies, B., Pugh, C.W., Ratcliffe, P.J., Katschinski, D.M. Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia. Circ Res. 2021 Apr 16;128(8):1208-1210. doi: 10.1161/CIRCRESAHA.120.318216.

  • Nanadikar, M.S., Vergel Leon, A.M., Borowik, S., Hillemann, A., Zieseniss, A., Belousov, V.V., Bogeski, I., Rehling, P., Dudek, J., Katschinski, D.M. O2 affects mitochondrial functionality ex vivo. Redox Biol. 2019 April;22:101152. doi: 10.1016/j.redox.2019.101152.

  • Swain, L., Kesemeyer, A., Meyer-Roxlau, S., Vettel, C., Zieseniss, A., Güntsch, A., Jatho, A., Becker, A., Nanadikar, M.S., Morgan, B., Dennerlein, S., Shah, A.M., El-Armouche, A., Nikolaev, V.O., Katschinski, D.M. Redox Imaging Using Cardiac Myocyte Specific Transgenic Biosensor Mice. Circ Res. 2016 Oct 14;119(9):1004-1016. doi: 10.1161/CIRCRESAHA.116.309551.

  • Zieseniss, A., Hesse, A.R., Jatho, A., Krull, S., Hölscher, M., Vogel, S., Katschinski, D.M. Cardiomyocyte-Specific Transgenic Expression of Prolyl-4-Hydroxylase Domain 3 Impairs the Myocardial Response to Ischemia. Cell Physiol Biochem. 2015;36(3):843-51. doi: 10.1159/000430260.

  • Vogler, M., Zieseniss, A., Hesse, A.R., Levent, E., Tiburcy, M., Heinze, E., Burzlaff, N., Schley, G., Eckardt, K.U., Willam, C., Katschinski, D.M. Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult. Pflugers Arch. 2015 Oct;467(10):2141-9. doi: 10.1007/s00424-014-1667-z.