"General and applied microbiology" (12 C, 14 WLH) [M.Bio.101]

Learning outcome: Evolution and phylogenetic system; morphology and cell biology; communities and biocoenosis of bacteria and archaea; gene expression and molecular control (transcription, translation); posttranslational control, protein stability and proteomics; genetic networks; molecular switches and signal transduction; microbial developmental biology; mechanisms of pathogenicity of important pathogens; development of new antimicrobial agents; diversity of the metabolism in bacteria and archaea as basis for biotechnological applications; industrial microbiology.
Acquisition of biomolecular, genetic, and biochemical techniques for manipulation and analysis of the model organisms used in the participating work groups through experiments from the fields of research of the respective work group, e.g. structural analysis and classification of bacteria, transformation, isolation of DNA, sequencing of DNA, diagnostic and Real-time PCR, fluorescence microscopy, enzyme assays, cloning, protein purification.

Core skills: Knowledge of microorganisms relevant for biotechnology and medicine, ability to identify these organisms and to analyse them with molecular methods.Independent acquisition of professional and critical dealing with knowledge from publications on current topics in microbiology.


Courses:
1. Lecture: »General and applied microbiology« (3 WLH)
2. Seminar: »General and applied microbiology« (1 WLH)
3. Methods course: »Signal transduction in bacteria« or
Methods course »Isolation and characterisation of biotechnologically relevant microorganisms« (10 WLH)

Examination: written examination covering lecture topics (90min, 90% of grade) and seminar presentation (15min, 10% of grade)
Prerequisite for examination: testified protocol (max. 10 pages) and oral presentation (ca. 15 min)
Examination requirements:Detailed knowledge in cell biology, biochemistry and genetics of procaryotic microorgansims. Deepened knowledge of molecular biological, genetic and biochemical techniques to analyze procaryotes. Ability to critically present and reflect scientific publications.


Selection options
elective-compulsory

Admission requirements
Can´t be combined with M.Bio.141

Recommended previous knowledge
none

Number of repeat examinations permitted
twice


Course frequency
each winter semester

Duration
1 semester

Language
English

Workload
360 h (194/164 h, Attendance time/Self-study time)

Person responsible for module
Prof. Dr. J. Stülke