In the neurosciences, Göttingen is known worldwide for research on the molecular mechanisms underlying synaptic function, which are being studied at all levels of complexity including isolated molecules, model synapses, small networks, and entire nervous systems. The scope of research has been extended to include disease models.

Core research activities of the program, hosted by the CMPB, are the molecular and cellular analysis of brain function, in particular the investigation of the mechanisms of (i) synaptic function, (ii) neuron-glia interactions, (iii) neuronal development/synaptogenesis, (iv) synaptic plasticity and network adaptation (v) synaptopathies leading to network dysfunctions (vi) neurodegenerative, neurological, and psychiatric diseases, (vii) nervous system regeneration. Projects employ in parallel biochemical, cell biological, genetic, morphological, physiological, and behavioral approaches and integrate genetic model organisms. The training program includes molecular/cellular neurobiology, biochemistry, molecular biology, cell staining/imaging, electrophysiology, systems physiology, light and electron microscopy, and genetics.