Publications
Mittendorf J., Niebisch J.M., Pierdzig L., Sun S., Petutschnig E.K., Lipka V. (2024) Differential contribution of Arabidopsis chitin receptor complex components to defense signaling and ubiquitination-dependent endocytotic removal from the plasma membrane. New Phytologist 244: 934–948.
Petutschnig E, Pierdzig L, Mittendorf J, Niebisch JM, Lipka V. (2023) A novel fluorescent protein pair facilitates FLIM-FRET analysis of plant immune receptor interaction under native conditions. Journal of Experimental Botany 75(3):746-759. doi: 10.1093/jxb/erad418.
Ricardi M.M., Wallmeroth N., Cermesoni C., Mehlhorn D.G., Richter S., Zhang L., Mittendorf J., Godehardt I., Berendzen K.W., von Roepenack-Lahaye E., Stierhof Y.D., Lipka V., Jürgens G., Grefen C. (2023) A tyrosine phospho-switch within the Longin domain of VAMP721 modulates SNARE functionality. Plant Journal 116(6): 1633-1651. doi: 10.1111/tpj.16451.
Ao K., Rohmann P.F.W., Huang S., Li L., Lipka V., Chen S., Wiermer M., Li X. (2023) Puncta-localized TRAF domain protein TC1b contributes to the autoimmunity of snc1. Plant Journal 114(3): 591-612. doi: 10.1111/tpj.16155.
Petutschnig E.K., Anders J., Stolze M., Meusel C., Hacke R., Much L., Schwier M., Gippert A.L., Kroll S., Fasshauer P., Wiermer M., Lipka V. (2022) EXTRA LARGE G-PROTEIN2 mediates cell death and hyperimmunity in the chitin elicitor receptor kinase 1-4 mutant. Plant Physiology, 189 (4) 2413–2431. doi.org/10.1093/plphys/kiac214
Barghahn S., Arnal G., Jain N., Petutschnig E.K., Brumer H. and Lipka V. (2021) Mixed Linkage β-1,3/1,4-Glucan Oligosaccharides Induce Defense Responses in Hordeum vulgare and Arabidopsis thaliana. Frontiers in Plant Science, 12: 682439 doi: 10.3389/fpls.2021.682439
Ao K., Tong M., Li L., Lüdke D., Lipka V., Chen S., Wiermer M. and Li X. (2021) SCFSNIPER7 controls protein turnover of unfoldase CDC48A to promote plant immunity. New Phytologist 229(5): 2795-2811. doi: 10.1111/nph.17071
Ghareeb H., El-Sayed M., Pound M., Tetyuk O., Hanika K., Herrfurth C., Feussner I. and Lipka V. (2020) Quantitative Hormone Signaling Output Analyses of Arabidopsis thaliana Interactions With Virulent and Avirulent Hyaloperonospora arabidopsidis Isolates at Single-Cell Resolution. Frontiers in Plant Science 11: 603693. doi: 10.3389/fpls.2020.603693
Schnorrenberg S., Ghareeb H., Frahm L., Grotjohann T., Jensen N., Teichmann T., Hell S.W., Lipka V. and Jakobs S. (2020) Live‐cell RESOLFT nanoscopy of transgenic Arabidopsis thaliana. Plant Direct 4(9): e00261 doi: 10.1002/pld3.261
Hématy K., Lim M., Cherk C., Piślewska-Bednarek M., Sanchez-Rodriguez C., Stein M., Fuchs R., Klapprodt C., Lipka V., Molina A., Grill E., Schulze-Lefert P., Bednarek P. and Somerville S. (2020) Moonlighting Function of Phytochelatin Synthase in Extracellular Defense against Fungal Pathogens. Plant Physiology 182(4): 1920-1932.
Hunziker P., Ghareeb H., Wagenknecht L., Crocoll C., Halkier B.A., Lipka V. and Schulz A. (2020) De novo indol-3-ylmethyl glucosinolate biosynthesis, and not long-distance transport, contributes to defence of Arabidopsis against powdery mildew. Plant Cell and Environment 43(6): 1571-1583
doi: 10.1111/pce.13766.
Rekhter D., Lüdke D., Ding Y., Feussner K., Zienkiewicz K., Lipka V., Wiermer M., Zhang Y., and Feussner I. (2019) Isochorismate-derived biosynthesis of the plant stress hormone salicylic acid. Science 365: 498-502.
Johnson J.M., Thürich J., Petutschnig E.K., Altschmied L., Meichsner D., Sherameti I., Dindas J., Mrozinska A., Paetz C., Scholz S.S., Furch A.C.U., Lipka V., Hedrich R., Schneider B., Svatoš A. and Oelmüller R. (2018) A Poly(A) Ribonuclease Controls the Cellotriose-Based Interaction between Piriformospora indica and Its Host Arabidopsis. Plant Physiology 176(3):2496-2514.
Erwig J., Ghareeb H., Kopischke M., Hacke R., Matei A., Petutschnig E.K. and Lipka V. (2017) Chitin-induced and CHITIN ELICITOR RECEPTOR KINASE1 (CERK1) phosphorylation-dependent endocytosis of Arabidopsis thaliana LYSIN MOTIF-CONTAINING RECEPTOR-LIKE KINASE5 (LYK5). New Phytologist 215(1): 382-396.
doi: 10.1111/nph.14592.
Genenncher B., Lipka V., Petutschnig E.K. and Wiermer M. (2017) Nucleoporin NUP88/MOS7 is required for manifestation of phenotypes associated with the Arabidopsis CHITIN ELICITOR RECEPTOR KINASE1 mutant cerk1-4. Plant Signal Behav 12(5): e1313378. doi: 10.1080/15592324.2017.1313378.
Johnson K.C., Zhao J., Wu Z., Roth C., Lipka V., Wiermer M. and Li X. (2017) The putative kinase substrate MUSE7 negatively impacts the accumulation of NLR proteins. Plant Journal 89(6): 1174-1183.
doi: 10.1111/tpj.13454.
Douchkov D., Lueck S., Hensel G., Kumlehn J., Rajaraman J., Johrde A., Doblin M.S., Beahan C.T., Kopischke M., Fuchs R., Lipka V., Niks R.E., Bulone V., Chowdhury J., Little A., Burton R.A., Bacic A., Fincher G.B. and Schweizer P. (2016) The barley (Hordeum vulgare) cellulose synthase-like D2 gene (HvCslD2) mediates penetration resistance to host-adapted and nonhost isolates of the powdery mildew fungus. New Phytologist 212(2): 421-433. doi: 10.1111/nph.14065.
Ghareeb H., Laukamm S., and Lipka V. (2016) COLORFUL-Circuit: A Platform for Rapid Multigene Assembly, Delivery, and Expression in Plants. Frontiers in Plant Science 7: 246.
doi: 10.3389/fpls.2016.00246
Fuchs R., Kopischke M., Klapprodt C., Hause G., Meyer A.J., Schwarzländer M., Fricker M.D., and Lipka V. (2016) Immobilized Subpopulations of Leaf Epidermal Mitochondria Mediate PENETRATION2-Dependent Pathogen Entry Control in Arabidopsis. Plant Cell 28: 130-145.
Antolín-Llovera M., Petutsching E.K., Ried M.K., Lipka V., Nürnberger T., Robatzek S. and Parniske M. (2014) Knowing your friends and foes--plant receptor-like kinases as initiators of symbiosis or defence. New Phytologist 204(4): 791-802.
Petutschnig E.K., Stolze M., Lipka U., Kopischke M., Horlacher J., Valerius O., Rozhon W., Gust A.A., Kemmerling B., Poppenberger B., Braus G.H., Nürnberger T. and Lipka V. (2014) A novel Arabidopsis CHITIN ELICITOR RECEPTOR KINASE 1 (CERK1) mutant with enhanced pathogen-induced cell death and altered receptor processing. New Phytologist 204(4): 955-967. doi: 10.1111/nph.12920
Huang Y., Minaker S., Roth C., Huang S., Hieter P., Lipka V., Wiermer M. and Li X. (2014) An E4 Ligase Facilitates Polyubiquitination of Plant Immune Receptor Resistance Proteins in Arabidopsis. Plant Cell 26: 485-496.
Reusche M., Truskina J., Thole K., Nagel L., Rindfleisch S., Tran V.T., Braus-Stromeyer S.A., Braus G.H., Teichmann T. and Lipka V. (2014) Infections with the vascular pathogens Verticillium longisporum and Verticillium dahliae induce distinct disease symptoms and differentially affect drought stress tolerance of Arabidopsis thaliana. Environmental and Experimental Botany 108: 23-37.
Tran V.T., Braus-Stromeyer S.A., Kusch H., Reusche M., Kaever A., Kühn A., Valerius O., Landesfeind M., Aßhauer K., Tech M., Hoff K., Centeno T.P., Stanke M., Lipka V. and Braus G.H. (2014) Verticillium transcription activator of adhesion Vta2 suppresses microsclerotia formation and is required for systemic infection of plant roots. New Phytologist 202(2): 565-581.
Huang Y., Chen X., Liu Y., Roth C., Copeland C., McFarlane H.E., Huang S., Lipka V., Wiermer M. and Li X. (2013) Mitochondrial AtPAM16 is required for plant survival and the negative regulation of plant immunity. Nature Communications 4: 2558.
Polle A., Janz D., Teichmann T. and Lipka V. (2013) Poplar genetic engineering: promoting desirable wood characteristics and pest resistance. Applied Microbiology & Biotechnology 97(13): 5669-5679.
Faulkner C., Petutschnig E., Benitez-Alfonso Y., Beck M., Robatzek S., Lipka V. and Maule A.J. (2013) LYM2-dependent chitin perception limits molecular flux via plasmodesmata. PNAS 110(22): 9166-9170.
Reusche M., Klásková J., Thole K., Truskina J., Novák O., Janz D., Strnad M., Spíchal L., Lipka V.* and Teichmann T.* (2013) Stabilization of cytokinin levels enhances Arabidopsis resistance against Verticillium longisporum. Molecular Plant Microbe Interactions 26(8): 850-860.
* co-corresponding authors
Kopischke M., Westphal L., Schneeberger K., Clark R., Ossowski S., Wewer V., Fuchs R., Landtag J., Hause G., Dörmann P., Lipka V., Weigel D., Schulze-Lefert P., Scheel D. and Rosahl S. (2012) Impaired sterol ester synthesis alters the response of Arabidopsis thaliana to Phytophthora infestans. The Plant Journal 73(3): 456-468. doi: 10.1111/tpj.12046.
Iven T., König S., Singh S., Braus-Stromeyer S.A., Bischoff M., Tietze L.F., Braus G.H., Lipka V., Feussner I. and Dröge-Laser W. (2012) Transcriptional activation and production of tryptophan-derived secondary metabolites in Arabidopsis roots contributes to the defense against the fungal vascular pathogen Verticillium longisporum. Molecular Plant 5(6): 1389-1402. doi: 10.1093/mp/sss1044.
Reusche M., Thole K., Janz D., Truskina J., Rindfleisch S., Drübert C., Polle A., Lipka V.* and Teichmann T. (2012). Verticillium Infection triggers VASCULAR-RELATED NAC DOMAIN7-Dependent de novo xylem formation and enhances drought tolerance in Arabidopsis. The Plant Cell 24: 3823-3837.
* corresponding author
König S., Feussner K., Schwarz M., Kaever A., Iven T., Landesfeind M., Ternes P., Karlovsky P., Lipka V. and Feussner I. (2012) Arabidopsis mutants of sphingolipid fatty acid α-hydroxylases accumulate ceramides and salicylates. New Phytologist 196(4): 1086-1097.
Wiermer M., Cheng Y.T., Imkampe J., Li M., Wang D., Lipka V. and Li X. (2012). Putative members of the Arabidopsis Nup107-160 nuclear pore sub-complex contribute to pathogen defense. Plant Journal 70: 796-808.
Willmann R., Lajunen H.M., Erbs G., Newman M.A., Kolb D., Tsuda K., Katagiri F., Fliegmann J., Bono J.J., Cullimore J.V., Jehle A.K., Götz F., Kulik A., Molinaro A., Lipka V., Gust A.A. and Nürnberger T. (2011) Arabidopsis lysin-motif proteins LYM1 LYM3 CERK1 mediate bacterial peptidoglycan sensing and immunity to bacterial infection. PNAS 108(49): 19824-19829.
Reichardt I., Slane D., El Kasmi F., Knöll C., Fuchs R., Mayer U., Lipka V. and Jürgens G. (2011) Mechanisms of functional specificity among plasma-membrane syntaxins in Arabidopsis. Traffic 12(9): 1269-1280.
Jacobs S., Zechmann B., Molitor A., Trujillo M., Petutschnig E., Lipka V., Kogel K.H. and Schäfer P. (2011) Broad-spectrum suppression of innate immunity is required for colonization of Arabidopsis roots by the fungus Piriformospora indica. Plant Physiology 156(2): 726-740.
Petutschnig E.K., Jones A.M., Serazetdinova L., Lipka U. and Lipka V. (2010) The Lysin Motif Receptor-like Kinase (LysM-RLK) CERK1 Is a Major Chitin-binding Protein in Arabidopsis thaliana and Subject to Chitin-induced Phosphorylation. Journal of Biological Chemistry 285(37): 28902-28911.
The latter was selected as a Paper of the Week and the first author, Elena K. Petutschnig, featured in an author profile:
http://www.jbc.org/content/285/37/28902/suppl/DC1/-/2
Todesco M., Balasubramanian S., Hu T.T., Traw M.B., Horton M., Epple P., Kuhns C., Sureshkumar S., Schwartz C., Lanz C., Laitinen R.A.E., Huang Y., Chory J., Lipka V., Borevitz J.O., Dangl J.L., Bergelson J., Nordborg M.and Weigel D. (2010) Natural allelic variation underlying a major fitness trade-off in Arabidopsis thaliana, Nature 465: 632-636.
Lipka U., Fuchs R., Kuhns,C., Petutschnig E. and Lipka V. (2010) Live and let die - Arabidopsis nonhost resistance to powdery mildews, European Journal of Cell Biology 89: 194-199.
Schornack S., Fuchs R., Huitema E., Rothbauer U., Lipka V.* and Kamoun S.* (2009) Protein mislocalization in plant cells using a GFP-binding chromobody, Plant Journal 60: 744-754.
* co-corresponding authors
Gimenez-Ibanez S., Hann D.R., Ntoukakis V., Petutschnig E., Lipka V.* and Rathjen J.P.* (2009) AvrPtoB targets the LysM receptor kinase CERK1 to promote bacterial virulence on plants, Current Biology 19: 423-429.
* co-corresponding authors
Lipka U., Fuchs R. and Lipka V. (2008) Arabidopsis non-host resistance to powdery mildews, Current Opinion in Plant Biology 11: 404-411.
Kwon C., Neu C., Pajonk S., Yun H.S., Lipka U., Humphry M.E., Bau S., Straus M., Rampelt H., El Kasmi F., Jürgens G., Parker J., Panstruga R.*, Lipka V.* and Schulze-Lefert P.* (2008) Co-option of a default secretory pathway for plant immune responses, Nature 451: 835-840.
* co-corresponding authors
Scheres B. and Lipka V. (2007) Plant cell biology – get your networks together, Current Opinion in Plant Biology 10: 546-548.
Lipka V., Kwon C. and Panstruga R. (2007) SNARE-Ware: The Role of SNARE-Domain Proteins in Plant Biology, Annual Reviews of Cell and Developmental Biology 23: 147-174.
Miklis M., Consonni C., Bhat R.A., Lipka V., Schulze-Lefert P. and Panstruga R. (2007) Barley Mlo modulates actin-dependent and actin-independent antifungal defence pathways at the cell periphery, Plant Physiology 144: 1132–1143.
Consonni C., Humphry M.E., Hartmann H.A., Livaja M., Durner J., Westphal L., Vogel J., Kemmerling B., Lipka V., Schulze-Lefert P., Somerville S.C. and Panstruga R. (2006) Conserved requirement for a plant host cell protein in powdery mildew pathogenesis. Nature Genetics 38: 716-720.
Shimada C., Lipka V., O’Connell R., Okuno T., Schulze-Lefert P. and Takano Y. (2006) Non-host resistance in Arabidopsis-Colletotrichum interactions acts at the cell periphery and requires actin filament function. Molecular Plant Microbe Interactions 19: 270-279.
Stein M., Dittgen J., Sanchez-Rodriguez C., Hou B.-H., Molina A., Schulze-Lefert P., Lipka V. and Somerville S. (2006) Arabidopsis PEN3/PDR8, an ATP binding cassette transporter, contributes to nonhost resistance to inappropriate pathogens that enter by direct penetration. Plant Cell 18: 731-746.
Lipka V., Dittgen J., Bednarek P., Bhat R.A., Stein M., Landtag J., Brandt W., Scheel D., Llorente F., Molina A., Wiermer M., Parker J., Somerville S. C. and Schulze-Lefert P. (2005) Pre- and post-invasion defenses both contribute to non-host resistance in Arabidopsis. Science 310: 1180-1183
[The latter two articles were featured in:
Ellis J. (2006) Insights into nonhost disease resistance: Can they assist disease control in agriculture? Plant Cell 18: 523-528]
Lipka V. and Panstruga R. (2005) Dynamic cellular responses in plant-microbe interactions. Current opinion in plant biology 8: 625-631
Nürnberger T. and Lipka V. (2005) Non-host resistance in plants: new insights into an old phenomenon. Molecular Plant Pathology 6: 335-345
Zimmerli L., Stein M., Lipka V., Schulze-Lefert P. and Somerville S.C. (2004) Host and nonhost pathogens elicit different jasmonate/ethylene responses in Arabidopsis. Plant Journal 40: 633-646
Jacobs* A. K., Lipka V.*, Burton R. A., Panstruga R., Strizhov N., Schulze-Lefert P. and Fincher G. B. (2003) An Arabidopsis thaliana callose synthase, GSL5, is required for wound and papillary callose formation. Plant Cell 15: 2503-2513
* shared first authors
Collins N. C., Thordal-Christensen H., Lipka V., Bau S., Kombrink E., Qiu J.-L., Hückelhoven R., Stein M., Freialdenhoven A., Somerville S. C. and Schulze-Lefert, P. (2003) SNARE protein mediated disease resistance at the plant cell wall. Nature 425: 973-977
Rushton P. J., Reinstaedler A., Lipka V., Lippok B.and Somssich I. E. (2002) Synthetic plant promoters containing defined regulatory elements provide novel insights into pathogen- and wound-induced signaling. Plant Cell 14: 749-762
Rademacher T., Haeusler R.E., Hirsch H.J., Zhang L., Lipka V., Weier D., Kreuzaler F.and Peterhaensel C. (2002) An engineered phosphoenolpyruvate carboxylase redirects carbon and nitrogen flow in transgenic potato plants. Plant Journal 32: 25-39
Haeusler R.E., Rademacher T., Li J., Lipka V., Fischer K.L, Schubert S., Kreuzaler F.and Hirsch H.J. (2001) Single and double overexpression of C4-cycle genes had differential effects on the pattern of endogenous enzymes, attenuation of photorespiration and on contents of UV protectants in transgenic potato and tobacco plants. Journal of Experimental Botany 52: 1785-1803
Lipka V., Haeusler R.E., Rademacher T., Li J., Hirsch H.J. and Kreuzaler F. (1999) Solanum tuberosum double transgenic expressing phosphoenolpyruvate carboxylase and NADP-malic enzyme display reduced electron requirement for CO2 fixation. Plant Science 144: 93-105
Panstruga R., Hippe-Sanwald S., Yeon-Kyeong L., Lataster M., Lipka V., Fischer R., Liao Y.C., Häusler R.E., Kreuzaler F.and Hirsch H.J. (1997) Expression and chloroplast-targeting of active phosphoenolpyruvate synthetase from Escherichia coli in Solanum tuberosum. Plant Science 127: 191-205