"Structural biochemistry" (12 C, 14 WLH) [M.Bio.106]
Learning outcome, core skills Methods in Structural Biochemistry, structure and function of biological macromolecules. Structure and folding of proteins, structure-function relationships, protein-protein and protein-nucleic acid complexes. Structure-based drug-design, molecular recognition. Handling of state of the art equipment, critical dealing with current biochemical topics, detailed analysis of experiments and their presentation. Independent acquisition of professional knowledge from publications by active participation in the seminar.
Examination requirements: knowledge of the basics in structural biochemistry, especially: * biochemical and analytic methods used in the characterization of proteins and macromolecular complexes * characteristics of selected proteins and protein complexes * the basics of structural resolution and the structural characteristics of proteins and nucleic acids
Courses:
1. Lecture:»Structural biochemistry« (3 WLH),
2. Seminar: »Structural biochemistry« (1 WLH),
3. Methods course: »Structural biology« (10 WLH)
Examination: Written examination (90min, 80% of grade), oral presentation within seminar (15min, 10% of grade) and protocol (max 20 pages, 10% of grade)
Prerequisite for examination: regular participation in practical course and protocol
Selection options
elective-compulsory
Admission requirements
can't be combined with key competence modules M.Bio.156 and M.Bio.166
Recommended previous knowledge
none
Number of repeat examinations permitted
twice
Course frequency
each summer-semester
Duration
1 semester
Language
English
Maximum number of students
20
Workload
360 h (196/164 h, Attendance time /Self-study time)
Person responsible for module
Prof. Dr. Ralf Ficner